Senolytic therapies
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Let's delve deeper into the topic of senolytic therapies and their potential role in promoting longevity. Senolytic therapies aim to target and eliminate senescent cells, which are essentially "zombie cells" that no longer divide or function properly but remain metabolically active. These cells accumulate with age and contribute to inflammation, tissue dysfunction, and the development of age-related diseases.
Recent studies have shown promising results using senolytic agents, such as dasatinib and quercetin, in clearing senescent cells from various tissues, leading to improved organ function, reduced inflammation, and increased overall healthspan in animal models. The potential benefits of senolytic therapies are vast, including the possible prevention or delay of age-related conditions like osteoarthritis, atherosclerosis, and neurodegenerative diseases.
However, it's essential to consider the challenges and questions that remain in the field of senolytic therapies. For instance, determining the optimal dosing regimen, safety profiles, and potential side effects is crucial to ensure these therapies are both effective and safe for human use. Additionally, we must consider the long-term implications of eliminating senescent cells and whether doing so may inadvertently impact other essential cellular processes.
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Anyone actually tried any of them?
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@ashley fasting can help induce autophagy. During autophagy, the body removes damaged cells and proteins, which include zombie cells. So if fasting counts